Iodoacetamide 98% stabilized

Supplier: Thermo Scientific Chemicals
Danger

Synonyms: 2-Iodoacetamide

Stabilization: Moistened with water ∼5-8%

A14715-14 A14715-14 A14715-06 A14715-06 A14715-22 A14715-22
AAA14715-14EA 120.53 USD
AAA14715-14 AAA14715-06 CAAAA14715-22 CAAAA14715-14 AAA14715-22 CAAAA14715-06
Iodoacetamide 98% stabilized
Iodoacetamide

Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation


2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.

Formula: ICH₂CONH₂
MW: 184.96 g/mol
Melting Pt: 92…95 °C (dried)
Storage Temperature: Refrigerator
MDL Number: MFCD00008028
CAS Number: 144-48-9
EINECS: 205-630-1
UN: 2811
ADR: "6.1",III

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