Cytochalasin B (from Helminthosporium dematioideum) ≥98% (by HPLC), Sigma-Aldrich®
Supplier: MilliporeSigma
Synonyms:
7(S),20(R)-Dihydroxy-16(R)-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13(E),21(E)-triene-1,23-dione
Cell-permeable fungal toxin
Inhibits cytoplasmic division by blocking the formation of contractile microfilaments. Inhibits cell movement and induces nuclear extrusion. Shortens actin filaments by blocking monomer addition at the fast-growing end of polymers. Inhibits glucose transport and platelet aggregation. Blocks adenosine-induced apoptotic body formation without affecting activation of endogenous ADP-ribosylation in leukemia HL-60 cells.
Soluble in MeOH or DMSO
Formula:
C₂₉H₃₇NO₅ |
MDL Number:
MFCD00077704 CAS Number: 14930-96-2 |
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