Doxorubicin hydrochloride, Sigma-Aldrich®
Synonyms:
(8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride
, Hydroxydaunorubicin Hydrochloride
An antitumor antibiotic and a highly effective myotoxin that inhibits topoisomerase II (IC50=0.1µM)
Binds to nucleic acids, presumably by specific intercalation into the DNA double helix, inhibiting nucleic acid synthesis. Induces apoptosis in rhabdomyosarcoma cell lines.
Formula:
C₂₇H₂₉NO₁₁·HCl MW: 579.98 g/mol |
MDL Number:
MFCD00077757 CAS Number: 25316-40-9 |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...