4',6'-Diamidino-2-phenylindole dihydrochloride (DAPI dihydrochloride), Calbiochem®
Supplier: MilliporeSigma
Synonyms:
2-(4-Amidinophenyl)indole-6-carboxamidine Dihydrochloride
, DAPI.2HCl
, 2-(4-Carbamimidoylphenyl)indole-6-carboximidamide Dihydrochloride
Cell-permeable DNA-binding dye specific for DNA that binds preferentially to DNA rich in adenine and thymine
Excitation maximum: 359nm. Emission maximum: 461nm.
Used in flow cytometry for measuring nuclear DNA content or for sorting isolated chromosomes. Useful for microscopic detection of nuclei and nuclear DNA in apoptotic cells. Can also be used to detect mycoplasma. A reversible inhibitor of S-adenosyl-L-methionine decarboxylase and diamine oxidase.
Formula:
C₁₆H₁₅N₅·2HCl MW: 350.25 g/mol |
MDL Number:
MFCD00012681 CAS Number: 28718-90-3 |
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