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Pepstatin A

Supplier: MP BIOMEDICALS (FKA ICN BIOMED
Soluble in ethanol (10 mg/mL with heat - colorless to hazy solution. To remove haziness, add up to 50 µL of glacial acetic acid per mL of ethanol. Insoluble in water.

MDL No.: MFCD00060740

Pepstatin A can be used in conjunction with E64-d and Leupeptin A to inhibit the degradation of autophagic cargo inside autophagosomes.

Pepstatin A is an inhibitor of acid proteases (aspartyl peptidases). It forms a 1:1 complex with proteases such as pepsin, renin, cathepsin D, bovine chymosin, and protease B (Aspergillus niger). The inhibitor is highly selective and does not inhibit thiol proteases, neutral proteases, or serine proteases. Solubilized γ-secretase and retroviral protease are also inhibited by Pepstatin A. It has been used to characterize proteases from several sources.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 mg 0219536880 IC19536880 Each (100mg) Retrieving Restricted
1 mg 0219536801 IC19536801 Each (1mg) Retrieving Restricted
250 mg 0219536883 IC19536883 Each (250mg) Retrieving Restricted
25 mg 0219536825 IC19536825 Each (25mg) Retrieving Restricted
5 mg 0219536805 IC19536805 Each (5mg) Retrieving Restricted
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SPECIFICATIONS

Type Oligopeptide
CAS No. 26305-03-3
Molecular Formula C₃₄H₆₃N₅O₉
Protein Pepstatin A
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