Polyethylene glycol 400, EMPROVE® ESSENTIAL Ph. Eur., SAFC®

Supplier: MilliporeSigma

Synonyms: PEG 400

8.17003.5000 8.17003.5000
EM8.17003.5000EA 468 USD
CA8.17003.5000 EM8.17003.5000
Polyethylene glycol 400, EMPROVE® ESSENTIAL Ph. Eur., SAFC®
Polyethylene glycol 400

Clear, viscous, almost colorless liquid. Hygroscopic. For pharmaceutical production.

Formula: H(OCH₂CH₂)nOH
MW: 400 g/mol
Boiling Pt: ∼250 °C (1013 hPa)
Melting Pt: 4…8 °C
Density: 1.13 g/cm³ (20 °C)
Flash Pt: 245 °C
Storage Temperature: Ambient
MDL Number: MFCD00081839
CAS Number: 25322-68-3
EINECS: 500-038-2

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Specification Test Results

Acidity or alkalinity Passes test
Appearance Clear, viscous almost colorless hygroscopic
Appearance of solution Passes test
Average Molecular Mass 380-420
Density (d20/20) About 1.120
Dioxane (GC) 10ppm max
Ethylene glycol and diethylene glycol 0.4% max
Ethylene glycole (acc. to ICH-guideline class 2) 620ppm max
Ethylene Oxide (GC) 1ppm max
Formaldehyde (HCHO) 30ppm max
Heavy metals 20ppm max
Hydroxyl value 264-300
Identity Passes test
Other Residual Solvents acc. to ICH guideline excluded by the manufacturing process
Reducing substances Passes test
Sulfated ash 0.2% max
Viscosity (20°C) 100-111mm²/s
Viscosity (20°C) 112-124mPa·s
Water 2.0% max

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