Carbenicillin disodium salt, free flowing powder


Synonyms: 6-[(Carboxyphenylacetyl)-amino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic Acid, 2Naα-Carboxybenzylpenicillin disodium salt

0219509201 0219509205 02195092.2
IC19509201EA 144.56 USD
IC19509201 IC19509205 IC195092.2
Carbenicillin disodium salt, free flowing powder
Carbenicillin disodium salt

Semi-synthetic antibiotic related to penicillin. It is a benzyl penicillin derivative with substitution of a-carboxyl group n the benzyl side chain. The product interferes with final cell wall synthesis of susceptible bacteria. It is completely ionized in the blood. Carbencillin disodium is about 50% reversibly protein bound in plasma and its tissue distribution is similar to other penicillins.

  • Presentation: Free Flowing Powder
  • pKa: (in water) 3.3
  • Soluble in water (50 mg/ ml) and alcohol

Though Carbencillin disodium has substantial in vitro activity against a variety of both gram-positive and gram-negative microorganisms, the most important aspect of its profile is in its antipseudomonal and antiproteal effect.

Used for selection of ampr transformed cells and to study the role of penicillin-sensitive transpeptidases in cell wall biosynthesis.

Carboxypenicillin antibiotic that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Analog to ampicillin. Antimicrobial spectrum: Gram-positive and Gram-negative bacteria, Pseudomonas.

Formula: C₁₇H₁₆N₂O₆S·2Na
MW: 422.363 g/mol
Storage Temperature: Refrigerator
CAS Number: 4800-94-6

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Specification Test Results

Identity Test Passes
Potency 650 µg/mg

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