Carbenicillin disodium salt, free flowing powderSupplier: MP BIOMEDICALS (FKA ICN BIOMED
6-[(Carboxyphenylacetyl)-amino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic Acid, 2Na
, α-Carboxybenzylpenicillin disodium salt
Semi-synthetic antibiotic related to penicillin. It is a benzyl penicillin derivative with substitution of a-carboxyl group n the benzyl side chain. The product interferes with final cell wall synthesis of susceptible bacteria. It is completely ionized in the blood. Carbencillin disodium is about 50% reversibly protein bound in plasma and its tissue distribution is similar to other penicillins.
- Presentation: Free Flowing Powder
- pKa: (in water) 3.3
- Soluble in water (50 mg/ ml) and alcohol
Though Carbencillin disodium has substantial in vitro activity against a variety of both gram-positive and gram-negative microorganisms, the most important aspect of its profile is in its antipseudomonal and antiproteal effect.
Used for selection of ampr transformed cells and to study the role of penicillin-sensitive transpeptidases in cell wall biosynthesis.
Carboxypenicillin antibiotic that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Analog to ampicillin. Antimicrobial spectrum: Gram-positive and Gram-negative bacteria, Pseudomonas.
MW: 422.363 g/mol
Storage Temperature: Refrigerator
Specification Test Results
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