Puromycin dihydrochloride ≥98% (by HPLC) cell culture tested, Calbiochem®, Sigma-Aldrich®
540411-100MG
540411-25MG
CA80503-310
CA80503-312
Puromycin dihydrochloride ≥98% (by HPLC) cell culture tested, Calbiochem®, Sigma-Aldrich®
Puromycin dihydrochloride
An aminonucleoside antibiotic that acts as a prokaryotic and eukaryotic protein synthesis inhibitor. Resembles the aminoacyl-adenylyl terminus of aminoacyl-tRNA and competes for binding to the A-site of the large ribosomal subunit.
- Protein synthesis inhibitor
- Inhibits translation by causing premature release of nascent polypeptide chains
- Induces DNA fragmentation in thymocytes and in human HL-60 leukemia cells
Specification Test Results
Purity (HPLC) | ≥98% |
Endotoxin | ≤10 EU/mg dry weight |
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