Puromycin dihydrochloride ≥98% (by HPLC) cell culture tested, Calbiochem®, Sigma-Aldrich®

540411-100MG 540411-25MG
CA80503-310 CA80503-312
Puromycin dihydrochloride ≥98% (by HPLC) cell culture tested, Calbiochem®, Sigma-Aldrich®
Puromycin dihydrochloride

An aminonucleoside antibiotic that acts as a prokaryotic and eukaryotic protein synthesis inhibitor. Resembles the aminoacyl-adenylyl terminus of aminoacyl-tRNA and competes for binding to the A-site of the large ribosomal subunit.


  • Protein synthesis inhibitor
  • Inhibits translation by causing premature release of nascent polypeptide chains
  • Induces DNA fragmentation in thymocytes and in human HL-60 leukemia cells

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Specification Test Results

Purity (HPLC) ≥98%
Endotoxin ≤10 EU/mg dry weight

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