Amphotericin B 250 µg/mL, yellow solution


091672346 091672348
10221-870EA 36.72 USD
10221-870 IC091672348
Amphotericin B 250 µg/mL, yellow solution
Amphotericin B

Amphotericin B is used as antifungal in cell culture media.
Amphotericin B is a polyene antifungal, antibiotic from Streptomyces sp. It has a high affinity for sterols, primarily ergosterols, of fungal and bacterial cell membranes. It is an antibiotic solution effective against yeast and other fungi. Amphotericin B may be toxic to some insect cell types. Amphotericin B, is an antimycotic.

  • Suitability: Suitable for cell culture
  • UV/Visible Absorbance: λmax: 345, 363, 382, 406 nm (methanol)(Lit.)
  • Formulation: It is formulated with deoxycholate and prepared in water for increased solubility.
  • pKa: 5.5, 10.0 (Lit.)
  • Foreign activity: Mycoplasma free.
  • Solubility: Slightly soluble in water; DMF/1M HCL 3/1: 49.00 - 51.00 mg/mL; Amphotericin B is insoluble in water at pH 6 to 7, but soluble in water at pH 2 or 11. It is soluble in DMSO (30 – 40 mg/mL) and in dimethylformamide (2 – 4 mg/mL).
  • Sterility: Sterile

Formula: C₄₇H₇₃NO₁₇
MW: 924.08 g/mol
Melting Pt: > 170 °C (dec., lit.)
Storage Temperature: Freezer
MDL Number: MFCD00877763
CAS Number: 1397-89-3

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