Llama IgG1 isotype control (FITC (Fluorescein Isothiocyanate))

Supplier: Rockland Immunochemicals
025-0240
76221-914EA 195.4 USD
76221-914
Llama IgG1 isotype control (FITC (Fluorescein Isothiocyanate))
Antibodies
Llama IgG1 isotype control Fluorescein Conjugate

  • control or standard reagent
  • multiplex, immunofluorescence microscopy, fluorescence based plate assays (FLISA) and fluorescent western blotting

Comparative studies of old world camelids (Camelus bactrianus and Camelus dromedarius) and new world camelids (Lama pacos, Lama glama and Lama vicugna) have shown that heavy-chain-only immunoglobulins represent between 35% - 70% of total IgG in the sera of all species. Such antibodies are homodimers of heavy chains that lack the CH1 domain of conventional antibodies and therefore do not interact with light chains, exhibiting a lower molecular weight ~100 kDa. In llama and other species of camelids, these heavy-chain-only immunoglobulins belong to the IgG2 and IgG3 subclasses.

All gamma chain camelid antibodies exhibiting the more conventional assembly of two light and two heavy chains with molecular weight ~150 kDa, belong to the IgG1 subclass.

Llama IgG1 FITC Conjugated isotype control can be utilized as a control or standard reagent in Flow Cytometry, immunofluorescence microscopy, fluorescence based plate assays (FLISA) and fluorescent western blotting experiments where determination of sample isotype is important.
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