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Human Recombinant IL-1-beta (from E. coli)

Supplier: Rockland Immunochemicals

009-F01-V25-1000 009-F01-V25-0100 009-F01-V25-0010 009-F01-V25-0002

75929-110EA 6969.19 USD

75929-110 75929-112 75929-114 75929-116

Human Recombinant IL-1-beta (from E. coli)

Proteins and Peptides

Recombinant Human IL-1-beta control protein

Control Protein
PCA Assays
ImmunoBlot

Interleukin-1 beta (IL-1β) is a pro-inflammatory cytokine produced in response to inflammatory agents by a variety of cells, including monocytes, macrophages, and dendritic cells (DCs). IL-1β and IL-1α are two distinct and independently regulated gene products that comprise IL-1 and signal through the Type 1 IL-1 receptor (IL-1R1). Although IL-1α is cell associated and IL-1β is secreted, they have nearly identical biological activity in that they induce adhesion molecule expression on epithelial cells, control fever induction, and play a role in arthritis and septic shock. Signaling activated by the IL-1R1 promotes these activities through a MYD88 signaling pathway similar to those associated with Toll receptors. Recombinant human IL-1β is a non-glycosylated protein, containing 153 amino acids, with a molecular weight of 17.4 kDa.

Interleukin-1-beta Recombinant Protein is suitable as a control for polyclonal or monoclonal anti-Interleukin-1-beta in immunological assays.

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