POR protein-GST fusion, Rockland Immunochemicals

Supplier: Rockland Immunochemical

009-001-T00 009-001-T00S
75931-112EA 690.06 USD
75931-112 75934-118
POR protein-GST fusion, Rockland Immunochemicals
Proteins and Peptides
POR control protein-GST fusion

  • Control Protein
  • PCA Assays
  • ImmunoBlot

POR is a flavoprotein that donates electrons to all microsomal P450 enzymes, including the steroidogenic enzymes P450c17, P450c21, and CYP51A1. POR encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain which binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes (1). POR has been linked with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome (2). POR Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Apoptosis/Autophagy, Cancer, and Metabolic Disorder research.

POR Protein is stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. POR Protein is suitable for use in Western Blot. Expect a band approximately ~102kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.
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