p73 gamma control protein-GST fusion
- Control Protein
- PCA Assays
- ImmunoBlot
p73 gamma is a member of the p53 family of transcription factors which are involved in cellular responses to stress and development. There are four isoforms of p73 (p73alpha, p73beta, p73delta and p73gamma) which differed in their abilities to form homodimeric and heterodimeric interactions with each other and with p53 (1). The p73 isoforms also differed in their abilities to activate transcription of the p21 (Waf1) promoter and to inhibit colony formation. The p73 protein is expressed at very low levels in normal tissues and is differentially expressed in a number of tumors. p73 is a stress-response gene that activates transcription of p53-responsive genes and inhibits cell growth in a p53-like manner by inducing apoptosis (2). p73gamma Protein is ideal for investigators involved in Signaling Proteins, Cell Cycle Proteins, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cell Cycle, Cellular Stress, Inflammation, JNK/SAPK Pathway, Metabolic Disorder, Neurobiology, and p38 Pathway research.
p73 gamma Protein is stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. p73 gamma Protein is suitable for use in Western Blot. Expect a band approximately ~85kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.
