Human Recombinant CDC42 (from E. coli)

Supplier: Rockland Immunochemicals
009-001-R60 009-001-R60S
10800-714EA 364.21 USD
10800-714 10800-716
Human Recombinant CDC42 (from E. coli)
Proteins and Peptides
CDC42 is a member of the Rho family of GTPases and is part of cellular pathways fundamental to growth, differentiation and apoptosis (1). Downstream targets for CDC42 include those that regulate the actin cytoskeleton (e.g. WASP) and cellular stress pathways (e.g. PAK) as well as the coatomer protein complex and PAR6. CDC42 is involved in the G(1)-S progression of the cell cycle. CDC42 and its downstream effector mDia3 are involved in bi-orientation and stabilization of spindle microtubules attachment to kinetochores and regulate chromosome alignment and segregation during mitosis (2). CDC42 Protein is ideal for investigators involved in Signaling Proteins, G-Proteins, Cancer, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, and Neurobiology research.
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