Ritonavir
Synonyms:
Thiazol-5-ylmethyl ((2S,3S,5S)-3-hydroxy-5-((S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanamido)-1,6-diphenylhexan-2-yl)carbamate
, Abbott 84538
, ABT-538
, A-84538
An orally bioavailable HIV-1 and HIV-2 protease inhibitor
Ritonavir is an orally bioavailable HIV-1 and HIV-2 protease inhibitor (EC₅₀ values are 0.022-0.13 and 0.16 μM, respectively). Through CYP3A4 inhibition, low doses of ritonavir can reduce the metabolism of concomitantly administered protease inhibitors, enhancing their bioavailability and efficacy.
Formula:
C₃₇H₄₈N₆O₅S₂ MW: 720.94 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00927142 CAS Number: 155213-67-5 |
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