Vincristine sulfate

Supplier: BioVision

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B2048-10 B2048-50
76269-488EA 90.18 USD InStock
76269-488 76269-490
Vincristine sulfate
Vincristine sulphate

Vincristine is a plant alkaloid isolated from Vinca Rosea that irreversibly blocks mitosis by binding to tubulin (Ki = 85 nM) and inhibiting tubulin polymerization. It arrests cell cycle in G2/M-phase by blocking mitotic spindle formation. Vincristine is exported from cells via the ATP-binding cassette transporter P-glycoprotein, but not by multidrug resistance-associated protein.

Formula: C₄₆H₅₈N₄O₁₄S
MW: 923,04
MDL Number: MFCD00084729
CAS Number: 2068-78-2
EINECS: 218-190-0
ADR: 6.1,II
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