ZLN024 hydrochloride ≥98% (by HPLC)
Synonyms:
2-[[2-(2-Bromo-4-methylphenoxy)ethyl]thio]pyrimidine hydrochloride
B2034-5
B2034-25
76269-466EA
145.93
USD
76269-466
76269-468
ZLN024 hydrochloride ≥98% (by HPLC)
ZLN024 hydrochloride
ZLN024 is an allosteric activator of AMP-activated protein kinase (AMPK) heterotrimers (EC₅₀s = 0.42 and 0.95 µM for α1β1γ1 and α2β1γ1, respectively. Inhibits dephosphorylation of AMPK Thr-172 by PP2Cα. Stimulates glucose uptake and fatty acid oxidation without increasing the ADP/ATP ratio.
Formula:
C₁₃H₁₃BrN₂OS.HCl MW: 361,69 g/mol |
CAS Number:
723249-01-2 |
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