BMS-986158 ≥98% (by HPLC)

Supplier: BioVision

Synonyms: (S)-2-(3-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-5-(phenyl(tetrahydro-2H-pyran-4-yl)methyl)-5H-pyrido[3,2-b]indol-7-yl)propan-2-ol

AB285435-5MG AB285435-1MG
76269-416EA 191.89 USD
76269-416 76269-418
BMS-986158 ≥98% (by HPLC)
BMS-986158

BMS-986158 is a potent bromodomain (BRD) and extra-terminal domain (BET) family inhibitor.  BMS-986158 binds to the acetyl-lysine binding site in the BRD of BET proteins, thereby preventing the interaction between BET proteins and acetylated histones. This disrupts chromatin remodeling and prevents the expression of certain growth-promoting genes, resulting in an inhibition of tumor cell growth.

Formula: C₃₀H₃₃N₅O₂ 
MW: 495,63 g/mol
CAS Number: 1800340-40-2 
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