AZD-5153 ≥98% (by HPLC)

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Synonyms: 6-hydroxynaphthalene-2-carboxylic acid(R)-4-(2-(4-(1-(3-Methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl)phenoxy)ethyl)-1,3-dimethylpiperazin-2-one 6-hydroxy-2-naphthoate4-[2-[4-[1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenoxy]ethyl]-1,3-dimethylpiperazin-2-one

B2020-5 B2020-25
76269-412EA 227.66 USD
76269-412 76269-414
AZD-5153 ≥98% (by HPLC)
AZD-5153

AZD-5153 is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor with a bivalent binding mode. AZD-5153 ligates two bromodomains in BRD4 simultaneously. Displays cellular and antitumor activity in preclinical hematologic tumor models.

Formula: C₂₅H₃₃N₇O₃∙C₁₁H₈O₃
MW: 667,8 g/mol
MDL Number: MFCD31382122
CAS Number: 1869912-40-2
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