MK-4827 (Tosylate) ≥98% (by HPLC)
Synonyms:
MK-4827 Tosylate
, (3S)-3-[4-[7-(Aminocarbonyl)-2H-indazol-2-yl]phenyl]piperidine Tosylate
, Niraparib tosylate
, (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide 4-methylbenzenesulfonate
, (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide 4-methylbenzenesulphonate
B2003-25
B2003-5
76269-368EA
204.31
USD
76269-368
76269-370
MK-4827 (Tosylate) ≥98% (by HPLC)
MK-4827 (Tosylate)
MK-4827 is a potent and selective PARP-1 and PARP-2 inhibitor with IC₅₀ values of 3.8 nM and 2.1 nM, respectively. It induces synthetic lethality in preclinical tumor models with loss of BRCA and PTEN function.
Formula:
C₁₉H₂₀N₄O·C₇H₈O₃S MW: 492,6 g/mol |
MDL Number:
MFCD28167748 CAS Number: 1038915-73-9 |
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