MK-4827 (Tosylate) ≥98% (by HPLC)

Synonyms: MK-4827 Tosylate(3S)-3-[4-[7-(Aminocarbonyl)-2H-indazol-2-yl]phenyl]piperidine TosylateNiraparib tosylate(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide 4-methylbenzenesulfonate(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide 4-methylbenzenesulphonate

B2003-25 B2003-5
76269-368EA 204.31 USD
76269-368 76269-370
MK-4827 (Tosylate) ≥98% (by HPLC)
MK-4827 (Tosylate)

MK-4827 is a potent and selective PARP-1 and PARP-2 inhibitor with IC₅₀ values of 3.8 nM and 2.1 nM, respectively. It induces synthetic lethality in preclinical tumor models with loss of BRCA and PTEN function.

Formula: C₁₉H₂₀N₄O·C₇H₈O₃S
MW: 492,6 g/mol
MDL Number: MFCD28167748
CAS Number: 1038915-73-9
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