AT-13387 ≥98% (by HPLC)
Supplier: BioVision
Synonyms:
(2,4-Dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone
, (2,4-dihydroxy-5-propan-2-ylphenyl)-[5-[(4-methylpiperazin-1-yl)methyl]-1,3-dihydroisoindol-2-yl]methanone
, Onalespib
AB273524-5MG
AB273524-25MG
76268-732EA
1049.53
USD
76268-732
76268-730
AT-13387 ≥98% (by HPLC)
AT-13387
AT-13387 is a synthetic, orally bioavailable and small-molecule inhibitor of heat shock protein 90 (Hsp90) with IC₅₀ value of 18 nM in A375 cells. Hsp90 acts as a “molecular chaperone” stabilizing and preventing the breakdown of key cancer-forming (oncogenic) proteins.
Formula:
C₂₄H₃₁N₃O₃ MW: 409,5 g/mol |
MDL Number:
MFCD18633198 CAS Number: 912999-49-6 |
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