AT-13387 ≥98% (by HPLC)

Supplier: BioVision

Synonyms: (2,4-Dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone(2,4-dihydroxy-5-propan-2-ylphenyl)-[5-[(4-methylpiperazin-1-yl)methyl]-1,3-dihydroisoindol-2-yl]methanoneOnalespib

AB273524-5MG AB273524-25MG
76268-732EA 1049.53 USD
76268-732 76268-730
AT-13387 ≥98% (by HPLC)
AT-13387

AT-13387 is a synthetic, orally bioavailable and small-molecule inhibitor of heat shock protein 90 (Hsp90) with IC₅₀ value of 18 nM in A375 cells. Hsp90 acts as a “molecular chaperone” stabilizing and preventing the breakdown of key cancer-forming (oncogenic) proteins.

Formula: C₂₄H₃₁N₃O₃
MW: 409,5 g/mol
MDL Number: MFCD18633198
CAS Number: 912999-49-6
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