ORY-1001 ≥98% (by HPLC)
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Warning
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Synonyms:
N1-((1R,2S)-2-phenylcyclopropyl)cyclohexane-1,4-diamine
, dihydrochloride
, trans-N1-(2-Phenylcyclopropyl)cyclohexane-1,4-diamine dihydrochloride
, RG-6016
ORY-1001 is a potent and selective inhibitor of LSD1 (IC₅₀ < 20 nM). It targets acute myeloid leukemia (AML) stem cells and significantly reduces tumor cell load while increasing survival time in mouse models of AML. ORY-1001 is in clinical trials for cancer treatment.
Formula:
C₁₅H₂₄Cl₂N₂ MW: 303,27 g/mol |
MDL Number:
MFCD28900684 CAS Number: 1431326-61-2 |
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