SB-415286 ≥98% (by HPLC)

Synonyms: 3-[(3-chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione3-((3-Chloro-4-hydroxyphenyl)amino)-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione

B1954-25 B1954-5
76268-708EA 758.88 USD
76268-708 76268-706
SB-415286 ≥98% (by HPLC)
SB-415286

SB-415286 is a potent, selective and ATP-competitive glycogen synthase kinase-3 (GSK-3) inhibitor (Ki = 31 nM for GSK-3α). Displays minimal activity against 24 other protein kinases (IC₅₀ > 10 μ M). Stimulates glycogen synthesis, gene transcription and is neuroprotective.

Formula: C₁₆H₁₀ClN₃O₅
MW: 359,73 g/mol
MDL Number: MFCD04039789
CAS Number: 264218-23-7
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