Serabelisib ≥98% (by HPLC)

Supplier: BioVision

Synonyms: INK1117TAK-117)MLN1117[6-(2-amino-5-benzoxazolyl)imidazo[1,2-a]pyridin-3-yl]-4-morpholinyl-methanone(6-(2-Aminobenzo[d]oxazol-5-yl)imidazo[1,2-a]pyridin-3-yl)(morpholino)methanone

AB235549-25MG AB235549-5MG
76268-586EA 980.59 USD
76268-586 76268-584
Serabelisib ≥98% (by HPLC)
Serabelisib

Serabelisib is a potent inhibitor of phosphoinositide 3-kinase α (PI3Kα) that is selective for p110α in vitro (IC₅₀ = 15 nM for PI3Kα vs. >1 µM for other isoforms, as well as for mTOR). MLN1117 inhibits AKT phosphorylation and growth in PIK3CA mutant breast cancer cells with IC₅₀ values around 2 μM, yet has no effect on cells lacking PTEN.

Formula: C₁₉H₁₇N₅O₃
MW: 363,34 g/mol
MDL Number: MFCD15146372
CAS Number: 1268454-23-4
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