Evofosamide ≥98%

Synonyms: TH302N,N'-bis(2-bromoethyl)-Phosphorodiamidic acidTH-3022-Bromo-N-[(2-bromoethylamino)-[(3-methyl-2-nitroimidazol-4-yl)methoxy]phosphoryl]ethanamine(1-methyl-2-nitro-1H-imidazol-5-yl)methyl ester

B1912-5 B1912-25
76270-326EA 671.3 USD
76270-326 76270-324
Evofosamide ≥98%
Evofosamide

Evofosfamide (TH-302) is an anticancer agent that is a hypoxia-activated prodrug that is created by linking the hypoxia-seeking 2-nitroimidazole moiety to the cytotoxic bromo-isophosphoramide mustard (Br-IPM). When evofosfamide is delivered to hypoxic regions of tumors, the DNA cross-linking toxin, Br-IPM, is released leading to cell death.

Formula: C₉H₁₆Br₂N₅O₄P
MW: 449,04 g/mol
MDL Number: MFCD22420822
CAS Number: 918633-87-1
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