Tanshinone IIA-sulfonic sodium ≥98% (by HPLC)
Synonyms:
Sodium 1,6,6-trimethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-sulphonate
, sulfotanshinone sodium II-A
, sulphotanshinone sodium II-A
, Sodium tanshinone IIA sulfonate
, Sodium 1,6,6-trimethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-sulfonate
, T06
, Sodium tanshinone IIA sulphonate
Sodium tanshinone IIA sulphonate (T06) is a water-soluble derivative of tanshinone IIA, that displays versatile biological properties. Recently, it has been shown to act as an ectosteric inhibitor of cathepsin K (CatK). T06 binds in an ectosteric side of Cathepsin K remote from its active site and selectively inhibits collagen degradation. It also inhibits bone resorption in ovariectomized mice.
Formula:
C₁₉H₁₇NaO₆S MW: 396,39 g/mol |
MDL Number:
MFCD09028094 CAS Number: 69659-80-9 |
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