U-73122
Synonyms:
1-[6-[((17beta)-3-Methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]pyrrole-2,5-dione
U-73122 is an Inhibitor of receptor-coupled phospholipase C-dependent processes in platelets and neutrophils via interfering with G protein-PLC interaction. A useful tool for probing the involvement of phospholipase C in receptor mediated cellular signaling and physiology. It also displays inhibitory activity against HIV-1 integrase (IC₅₀ = 7 µM). Cell permeable.
Formula:
C₂₉H₄₀N₂O₃ MW: 464.65 g/mol |
MDL Number:
MFCD12910450 CAS Number: 112648-68-7 |
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