NVS-SM1 ≥98% (by HPLC)

Synonyms: (6Z)-3-(1H-pyrazol-4-yl)-6-[3-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-1H-pyridazin-6-ylidene]cyclohexa-2,4-dien-1-oneBranaplamLMI070

B1844-5 B1844-25
76269-750EA 204.31 USD
76269-750 76269-752
NVS-SM1 ≥98% (by HPLC)
NVS-SM1

NVS-SM1, also known as LMI070, is a highly potent, selective small molecule SMN2 splicing modulator with potential for treating spinal muscular atrophy. It works by increasing the amount of functional survival of motor neuron protein produced by the SMN2 gene through modifying its splicing pattern.

Formula: C₂₂H₂₇N₅O₂
MW: 393,49 g/mol
MDL Number: MFCD29472288
CAS Number: 1562338-42-4
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