Arecolinium bromide
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Warning
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Synonyms:
Arecoline hydrobromide
B1824-500
B1824-100
76270-858EA
321.07
USD
76270-858
76270-856
Arecolinium bromide
Arecolinium bromide
Arecoline is a covalent inhibitor of ACAT1 which binds to and disrupts only ACAT1 tetramers (IC₅₀ = 11.1 μM). ACAT2 and DLAT are not inhibited. Treatment of xenograft nude mice with Arecoline resulted in a dose-dependent reduction in tumor mass. Agonist at muscarinic acetylcholine receptors M1 – M5 (EC₅₀ in the range of 7-410 nM). May be effective in dementia.
Formula:
C₈H₁₄BrNO₂ MW: 236.11 g/mol |
MDL Number:
MFCD00039041 CAS Number: 300-08-3 |
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