Ryuvidine ≥98%

Supplier: BioVision

Synonyms: 2-Methyl-5-[(4-methylphenyl)amino]-4,7-benzothiazoledione

AB254235-1MG B1808-5
76269-902EA 209.37 USD
76269-902 76269-904
Ryuvidine ≥98%
Ryuvidine

Ryuvidine is a potent inhibitor of SET domain-containing protein 8 (SETD8) (IC₅₀ = 0.5 µM) that suppresses monomethylation of H4K20 in vitro. It displays weak inhibiton against cyclin-dependent kinase 4 (Cdk4; IC₅₀ = 6 µM for Cdk4/cyclin D1). Induces S phase accumulation in HEK293T cells. Cytotoxic against a range of human cancer cells.

Formula: C₁₅H₁₂N₂O₂S
MW: 284,33 g/mol
CAS Number: 265312-55-8
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