Pexmetinib ≥98%

Synonyms: ARRY-614Pexmetinib(Z)-N-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-N'-(5-fluoro-2-((1-(2-hydroxyethyl)-1H-indazol-5-yl)oxy)benzyl)carbamimidic acid1-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(5-fluoro-2-((1-(2-hydroxyethyl)-1H-indazol-5-yl)oxy)benzyl)ureaARRY6141-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[[5-fluoro-2-[1-(2-hydroxyethyl)indazol-5-yl]oxyphenyl]methyl]ureaARRY 614

B1711-25 B1711-5
76268-502EA 671.3 USD
76268-502 76268-500
Pexmetinib ≥98%
Pexmetinib

Pexmetinib (ARRY-614) is a potent inhibitor of cytokine synthesis, via the dual inhibition of p38 mitogen-activated protein kinase (MAPK), and Tie2/Tek receptor tyrosine kinase.

Formula: C₃₁H₃₃FN₆O₃
MW: 556,63 g/mol
MDL Number: MFCD28502055
CAS Number: 945614-12-0
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