Dovitinib lactate ≥98% (by HPLC)

Warning

Synonyms: Dovitinib lactatemultitargeted receptor tyrosine kinase inhibitorDovitinibCHIR 2584-amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 2-hydroxypropanoate hydrateTKI-258TKI258TKI 258CHIR258CHIR-258

B1615-5 B1615-25
76270-814EA 391.11 USD
76270-814 76270-812
Dovitinib lactate ≥98% (by HPLC)
Dovitinib lactate

Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGF-1R and HER2 in cell-free assays.

Formula: C₂₄H₂₉FN₆O₅
MW: 500,53 g/mol
MDL Number: MFCD16038433
CAS Number: 915769-50-5
https://us.vwr.com/stibo/web/std.lang.all/17/90/24101790.jpg

Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR