GDC-0152 ≥98% (by HPLC)

Synonyms: GDC 0152(S)-1-((S)-2-Cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-N-(4-phenyl-1,2,3-thiadiazol-5-yl)pyrrolidine-2-carboxamideGDC0152(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-(4-phenylthiadiazol-5-yl)pyrrolidine-2-carboxamide

B1602-5 B1602-25
76270-614EA 787.84 USD
76270-614 76270-612
GDC-0152 ≥98% (by HPLC)
GDC-0152

GDC-0152 is a potent small molecule antagonist of XIAP-BIR3, ML-IAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 28 nM, 14 nM, 17 nM and 43 nM, respectively; less affinity shown to cIAP1-BIR2 and cIAP2-BIR2. Phase 1.

Formula: C₂₅H₃₄N₆O₃S
MW: 498,64 g/mol
MDL Number: MFCD26142660
CAS Number: 873652-48-3
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