Fevipiprant ≥98% (by HPLC)

Synonyms: 2-(2-Methyl-1-(4-(methylsulphonyl)-2-(trifluoromethyl)benzyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acidQAW039NVP-QAW0392-(2-Methyl-1-(4-(methylsulfonyl)-2-(trifluoromethyl)benzyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid

B1588-25 B1588-5
76270-406EA 577.91 USD
76270-406 76270-404
Fevipiprant ≥98% (by HPLC)
Fevipiprant

Fevipiprant is a prostaglandin D2 (PGD2) receptor antagonist with a Kd value of 1.14 nM for CRTH2/DP2. It has been shown to inhibit PGD2-stimulated human eosinophil shape change in whole blood assays (IC₅₀ = 0.44 nM) and to inhibit PGD2-induced cytokine release in human Th2 cells (IC₅₀s = 2.56 and 1.4 nM for IL-5 and IL-13, respectively). This compound has undergone testing in a phase II clinical study in uncontrolled allergic asthma.

Formula: C₁₉H₁₇F₃N₂O₄S
MW: 426,41 g/mol
MDL Number: MFCD28963975
CAS Number: 872365-14-5
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