Dexamethasone, white powder, Cell Culture Grade

Supplier: MP BIOMEDICALS (FKA ICN BIOMED
Danger

Synonyms: Dexamethasonum9-Fluor-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadien-3,20-dion

0219456191 0219456125 0219456190 0219456180
76204-370EA 362.78 USD
76204-370 76204-046 76204-368 76204-136
Dexamethasone, white powder, Cell Culture Grade
Dexamethasone

Dexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S transition in osteoblasts and inhibition of phosphorylation of Rb protein. Dexamethasone has been observed to induce apoptosis in human thymocytes and eosinophils but to inhibit apoptosis in neutrophils.


  • Grade : Cell culture reagent
  • Suitability : Suitable for Cell Culture
  • Key Applications : Anti-inflammatory
  • Application Areas : Cell Biology & Analysis
  • Product Type : Biochemicals
  • Biochemical Category : Pharmaceuticals
  • Chemical Class : Pharmaceuticals
  • Optical Rotation : (c=1, dioxane)+72 ° to +80 °
  • Refractive Index : 76 ° (C=1, Dioxane) (Lit.)
  • Presentation : White Powder
  • Loss on Drying : ≤0.5%
  • Solubility : Slightly soluble in water (10 mg/100 mL), ethanol (1 mg/mL), chloroform; sparingly soluble in acetone, alcohol, dioxane, and methanol; very slightly soluble in ether.


Storage: protect from light.

Formula: C₂₂H₂₉FO₅
MW: 392.47 g/mol
Melting Pt: 262...264 °C (lit.)
Storage Temperature: Ambient
MDL Number: MFCD00064136
CAS Number: 50-02-2
https://us.vwr.com/stibo/web/std.lang.all/53/07/36275307.jpg

Order Now

Specification Test Results

Identity Test Passes
FTIR Conforms to Standard
Loss on Drying 0.5%
Optical Rotation +72° to +80° (c=1, dioxane)

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR