Acetylated p53 (Human) ELISA Kit, BioVision, Inc.

Supplier: BioVision
E4531-100
76236-028EA 834.77 USD
76236-028
Acetylated p53 (Human) ELISA Kit, BioVision, Inc.
A sandwich ELISA kit for the quantitative measurement of Acetylated p53 in biological fluids.

  • Easy, convenient and time-saving method to measure the level of Acetyl-p53 in human serum, plasma, tissue homogenates, culture supernatants and other biological fluids.
  • Detection Range: 46.875 - 3000 pg/ml
  • Sensitivity: < 28.125 pg/ml
  • Assay Precision: Intra-Assay: CV < 8%; Inter-Assay: CV < 10%
  • This assay has high sensitivity and excellent specificity for detection of Acetyl-p53. No significant cross-reactivity or interference between Acetyl-p53 and analogues was observed.

The tumor suppressor protein p53 is one of the key players in cancer biology. DNA damage and oxidative stress signals lead to p53 posttranslational modifications and stabilization by binding to its consensus sequence, the p53 response element. Stabilized p53 can interact with other transcriptional regulators for the induction of p53-responsive targets involved in cell cycle progression, cell senescence, or apoptotic cell death. Because the expression and activity of p53 are frequently altered in human cancers, p53 becomes an important drug target as well as a biomarker in carcinogenesis. BioVision’s Acetylated p53 ELISA kit is a sandwich ELISA assay for the quantitative measurement of Acetylated p53 in human serum, plasma and cell culture supernatants. The density of color is proportional to the amount of Acetylated p53 captured from the samples.
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