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Anti-KRT8 & KRT18 Mouse Monoclonal Antibody (R-PE) [clone: Clone B22.1 B23.1]

Supplier: Biotium
BNCR1221-250
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.

Type: Primary
Antigen: KRT8 & KRT18
Clonality: Monoclonal
Clone: Clone B22.1 B23.1
Conjugation: R-PE
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
250 μL BNCR1221-250 75920-728 Each (250µl) Retrieving Restricted

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SPECIFICATIONS

Antigen Symbol KRT8 & KRT18
Antigen Name Cytokeratin 8/18
Reactivity Human
Conjugation RPE (R-Phycoerythrin)
Clonality Monoclonal
Antibody Type Primary
Clone B22.1 B23.1
Host Mouse
Isotype IgG1, kappa
Western Blot Yes
ImmunoFluorescence Yes
Gene ID Unigene ID: 533782 , 708445 (CK8); 406013 (CK18)
Concentration 0.1 mg/mL
Storage Buffer PBS/0.1% BSA/0.05% azide
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