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Anti-KRT8 Mouse Monoclonal Antibody (Unconjugated, BSA-and azide-free) [clone: Clone B22.1]

Supplier: Biotium
BNUM1219-50
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular (ring-like, perinuclear) from ductal (peripheral-predominant) carcinoma of the breast.

Type: Primary
Antigen: KRT8
Clonality: Monoclonal
Clone: Clone B22.1
Conjugation: Unconjugated, BSA-and azide-free
Epitope:
Host: Mouse
Isotype: IgG, kappa
Reactivity: Cow, Human, Pig, Rabbit, Sheep




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
50 μL BNUM1219-50 75923-210 Each (50µl) Retrieving Restricted

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SPECIFICATIONS

Antigen Symbol KRT8
Antigen Name Cytokeratin 8
Reactivity Human, Sheep, Cow, Rabbit, Pig
Conjugation Unconjugated
Clonality Monoclonal
Antibody Type Primary
Clone B22.1
Host Mouse
Isotype IgG, kappa
Gene ID Unigene ID: 533782 , 708445
Concentration 1 mg/mL
Storage Buffer PBS, no BSA, no azide
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