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Anti-PTH Mouse Monoclonal Antibody (CF680R) [clone: Clone PTH/1175]

Supplier: Biotium
BNC811175-100 BNC811175-500
The epitope of this MAb maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2 levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®680R is a near-infrared fluorescent dye (Ex/Em 680/701 nm) with unrivaled photostability. It also is validated in super-resolution imaging by STED and single-molecule spectroscopy.

Type: Primary
Antigen: PTH
Clonality: Monoclonal
Clone: Clone PTH/1175
Conjugation: CF680R
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Human




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 μL BNC811175-100 75973-524 Each (100µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

500 μL BNC811175-500 75973-526 Each (500µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen Symbol PTH
Antigen Name PTH / Parathyroid Hormone
Reactivity Human
Conjugation CF™ 680R
Clonality Monoclonal
Antibody Type Primary
Clone PTH/1175
Host Mouse
Isotype IgG2b, kappa
ImmunoChemistry Yes
ImmunoFluorescence Yes
Gene ID Unigene ID: 37045
Concentration 0.1 mg/mL
Storage Buffer PBS/0.1% BSA/0.05% azide
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