Anti-CEACAM1 & CEACAM5 Mouse Monoclonal Antibody (CF405S) [clone: C66/1030]

Supplier: Biotium

BNC041030-500 BNC041030-100
75916-772EA 197.58 USD
75916-772 75916-774
Anti-CEACAM1 & CEACAM5 Mouse Monoclonal Antibody (CF405S) [clone: C66/1030]
Antibodies
This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA positive) from pleural mesotheliomas (rarely or weakly CEA positive) . Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: CEACAM1 & CEACAM5
Clonality: Monoclonal
Clone: C66/1030
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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