This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®680 is a near-infrared fluorescent dye (Ex/Em 681/698 nm). It yields the brightest conjugates among spectrally similar dyes, and is validated in super-resolution imaging by STORM.
Type: Primary
Antigen: CD47
Clonality: Monoclonal
Clone: IAP/964 B6H12.2
Conjugation: CF680
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human, Mouse