Anti-MUC6 Mouse Monoclonal Antibody (CF405M) [clone: CLH5]

BNC050891-500 BNC050891-100
75962-850EA 179 USD
75962-850 75962-852
Anti-MUC6 Mouse Monoclonal Antibody (CF405M) [clone: CLH5]
Antibodies
The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405M is a blue fluorescent dye (Ex/Em 408/452 nm) with superior brightness and photostability compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: MUC6
Clonality: Monoclonal
Clone: Clone CLH5
Conjugation: CF405M
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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