Anti-AR Mouse Monoclonal Antibody (CF660R) [clone: AR441]

BNC610881-100 BNC610881-500
75881-848EA 494 USD
75881-848 75881-846
Anti-AR Mouse Monoclonal Antibody (CF660R) [clone: AR441]
Antibodies
This antibody recognizes a protein of 110 kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®660R is a far-red fluorescent dye (Ex/Em 663/682 nm) with superior brightness and unrivaled photostability among spectrally similar dyes.

Type: Primary
Antigen: AR
Clonality: Monoclonal
Clone: AR441
Conjugation: CF660R
Epitope:
Host: Mouse
Reactivity: Human
Isotype: IgG1, kappa
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