Anti-ALPP Mouse Monoclonal Antibody (CF543) [clone: GM022]

BNC430874-500 BNC430874-100
75970-512EA 179 USD
75970-512 75970-514
Anti-ALPP Mouse Monoclonal Antibody (CF543) [clone: GM022]
Antibodies
This antibody recognizes a 70 kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP This antibody recognizes germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®543 is an orange fluorescent dye (Ex/Em 541/560 nm) designed for the 543 nm laser line. It yields the brightest conjugates among spectrally similar dyes.

Type: Primary
Antigen: ALPP
Clonality: Monoclonal
Clone: Clone GM022
Conjugation: CF543
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Human
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR