Anti-CD99 Mouse Monoclonal Antibody (CF770) [clone: HO36-1.1]

BNC700869-100 BNC700869-500
75909-080EA 511.96 USD
75909-080 75909-078
Anti-CD99 Mouse Monoclonal Antibody (CF770) [clone: HO36-1.1]
Antibodies
This antibody recognizes a sialoglycoprotein of 27-32 kDa, identified as CD99, or MIC2 gene product, or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins, which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32 kDa (p30/32).Although its function is not fully understood, CD99 is implicated in various cellular processes including homotypic aggregation of T cells, upregulation of T cell receptor and MHS molecules, apoptosis of immature thymocytes and leukocyte diapedesis.CD99 is expressed on the cell membrane of some lymphocytes, cortical thymocytes, and granulosa cells of the ovary. Most pancreatic islet cells, Sertoli cells of the testis, and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing's sarcoma cells and primitive peripheral neuroectodermal tumors. This MAb shows a very similar reactivity to other CD99 MAbs (e.g. O13, 12E7, or HBA-71) and is excellent for immunohistochemical staining of formalin-fixed, paraffin-embedded tissues.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®770 is a near-infrared fluorescent dye (Ex/Em 770/797 nm) with exceptional brightness for in vivo imaging or near-IR western blotting.

Type: Primary
Antigen: CD99
Clonality: Monoclonal
Clone: Clone HO36-1.1
Conjugation: CF770
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human, Rat
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