Anti-CD5 Mouse Monoclonal Antibody (CF543) [clone: C5/473 CD5/54/F6]

BNC430748-500 BNC430748-100
75911-848EA 179 USD
75911-848 75911-850
Anti-CD5 Mouse Monoclonal Antibody (CF543) [clone: C5/473 CD5/54/F6]
Antibodies
This antibody recognizes a 67 kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma ( ) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®543 is an orange fluorescent dye (Ex/Em 541/560 nm) designed for the 543 nm laser line. It yields the brightest conjugates among spectrally similar dyes.

Type: Primary
Antigen: CD5
Clonality: Monoclonal
Clone: Clone C5/473 CD5/54/F6
Conjugation: CF543
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Cow, Human, Rabbit, Rat
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR