Anti-CD5 Mouse Monoclonal Antibody (HRP) [clone: CD5/54/F6]

BNCH0746-500 BNCH0746-100
75914-146EA 179 USD
75914-146 75914-148
Anti-CD5 Mouse Monoclonal Antibody (HRP) [clone: CD5/54/F6]
Antibodies
This antibody recognizes a 67 kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma ( ) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.

Type: Primary
Antigen: CD5
Clonality: Monoclonal
Clone: Clone CD5/54/F6
Conjugation: HRP
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Chicken, Cow, Guinea Pig, Horse, Human, Monkey, Pig, Rabbit, Rat
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