Anti-PTPRC Mouse Monoclonal Antibody (CF594) [clone: 2B11 PD7/26]

Supplier: Biotium

BNC940745-500 BNC940745-100
75914-732EA 197.58 USD
75914-732 75914-734
Anti-PTPRC Mouse Monoclonal Antibody (CF594) [clone: 2B11 PD7/26]
Antibodies
This antibody recognizes the CD45 leukocyte common antigen (LCA) family which comprises at least four isoforms of membrane glycoproteins (220, 205, 190, 180 kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues. The intracellular portions of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms. A positive result with this MAb is highly indicative of lymphoid or myeloid origin. Certain types of lymphoid neoplasms may lack CD45 (Hodgkin lymphoma, some T-cell lymphomas, and some leukemias) so its absence does not rule out a hematolymphoid tumor. This antibody is expressed almost exclusively by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes as well as plasma cell precursors.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: PTPRC
Clonality: Monoclonal
Clone: Clone 2B11 PD7/26
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG's
Reactivity: Dog, Human
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