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Anti-PAX6 Mouse Monoclonal Antibody (Alkaline Phosphatase) [clone: Clone PAX6/498]

Supplier: Biotium
BNCAP0498-500 BNCAP0498-100
Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.

Type: Primary
Antigen: PAX6
Clonality: Monoclonal
Clone: Clone PAX6/498
Conjugation: Alkaline Phosphatase
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Chicken, Human, Mouse, Rat




 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 μL BNCAP0498-100 75968-202 Each (100µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

500 μL BNCAP0498-500 75968-204 Each (500µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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SPECIFICATIONS

Antigen Symbol PAX6
Antigen Name PAX6
Reactivity Rat, Human, Mouse, Chicken Chicken, Mouse, Human, Rat
Conjugation AP (Alkaline Phosphatase)
Clonality Monoclonal
Antibody Type Primary
Clone PAX6/498
Host Mouse
Isotype IgG1, kappa
Western Blot Yes
ImmunoFluorescence Yes
Gene ID Unigene ID: 611376
Concentration 0.1 mg/mL
Storage Buffer PBS/0.1% BSA/0.05% azide
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