This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81 kDa) and PR-B (116 kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®680 is a near-infrared fluorescent dye (Ex/Em 681/698 nm). It yields the brightest conjugates among spectrally similar dyes, and is validated in super-resolution imaging by STORM.
Type: Primary
Antigen: PGR
Clonality: Monoclonal
Clone: Clone PR484
Conjugation: CF680
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human